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Sex differences in the incidence of depression and antidepressant treatment responses are well documented. Depression is twice as common in women as in men. Recent studies indicate that low levels of leptin, an adipocyte-derived hormone, are associated with increased symptoms of depression in women. Leptin has been shown to produce antidepressant-like effects in male rodents.
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Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page. Its negative prognostic value has been proven in many types of cancer. Immunohistochemistry IHC was used to evaluate marker expression in tumor cells. The site of Akt phosphorylation seems to have gender-dependent impact on survival in STS patients. Soft tissue sarcomas STS are malignant tumors arising from extraskeletal connective tissues.
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